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[International Cooperation][BioMedicine] International Study of over 1 Million Confirms Body Weight Influences Risk of Death in Asians

Posted by techman 
[International Cooperation][BioMedicine] International Study of over 1 Million Confirms Body Weight Influences Risk of Death in Asians (Chinese Version)

Academia Sinica Newsletter (2011/03/22) The Asian Cohort Consortium (ACC) including Dr. Yuan-Tsong CHEN and Dr. Chen-Yang SHEN, principal investigators at the Taiwan Biobank and the Institute of Biomedical Sciences, Academia Sinica, as well as researchers from Japan, Korea, China, Singapore, India and Bengal, recently found that being underweight is significantly associated with increased risk of death across Asia, while high body mass index (BMI) is associated with a higher risk of death only in East Asian populations. The study, which pooled data from more than 1.1 million people, was reported in the February 24, 2011, issue of The New England Journal of Medicine.

The researchers explored the correlation between Body Mass Index (BMI), an index of obesity, and mortality in 19 Asian cohorts over an average of 9.2 years. They found that in East Asians (Chinese, Japanese, and Koreans) mortality was lowest among people with a BMI in the range of 22.6 to 27.5. The risks were significantly higher among people with BMI levels either higher or lower than that range – increasing by a factor of up to 1.5 among those with a BMI 35.0 and by a factor of 2.8 among those with a BMI of 15.0 or less. A similar U-shaped association was also seen between BMI and mortality due to cancer, cardiovascular diseases, and other causes of death. High BMI was not, however, found to be associated with higher risk of death in Indian and Bangladeshi cohorts.

Up until now most studies exploring the association between BMI and mortality have been conducted in populations of European origin. The ACC study aimed to evaluate the same association between BMI and mortality, specifically in an Asian population. The study is one of the largest of its kind in the world and the findings are expected to impact public health policy in Asian countries and provide essential and critical information for implementing weight control program in the public in Taiwan.

The full text entitled, "Association between Body-Mass Index and Risk of Death in More Than 1 Million Asians" is available at New England Journal of Medicine website at: http://www.nejm.org/doi/full/10.1056/NEJMoa1010679

Media contacts:
Dr. Chen-Yang SHEN, Taiwan Biobank and the Institute of Biomedical Sciences, Academia Sinica
(Tel) +886-2-2652-3043
Mei-Hui LIN, Office of Public Affairs, Central Office of Administration, Academia Sinica
(Tel) +886-2-2789-8821, (Fax) +886-2-2782-1551, (M) 0921-845-234 mhlin313@gate.sinica.edu.tw


Further Information:
Academia Sinica Newsletter 2011/03/22

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Edited 1 time(s). Last edit at 03/22/2011 09:17AM by techman.
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