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[H1N1] 臺大校訊公佈H1N1新型流感定義

[H1N1] 臺大校訊公佈H1N1新型流感定義

本期(第962期)臺大校訊公佈H1N1新型流感的定義,分臨床條件、檢驗條件以及流行病學條件等歸準,定義病例分類判準。

臨床條件(Clinical criteria): 具有急性發燒呼吸道疾病(Acute febrile respiratory illness)(發燒超過攝氏38℃),且其臨床症狀包括從輕微的類流感(influenza-like illness)到較為嚴重的肺炎(pneumonia)等。

檢驗條件(Laboratory criteria): 經中央主管機關或其委託之病毒合約實驗室,檢出H1N1新型流感病毒陽性,其檢驗方法包括下列任何一項: 1. real-time RT-PCR、2.病毒培養、3.H1N1新型流感病毒中和抗體4倍上升。檢驗方法必需依照目前最新之檢驗指引進行檢驗。

流行病學條件(Epidemiology criteria)具有下列任一個條件:

一、曾經與確定病例或極可能病例具有密切接觸(close contact),即照護、同住、或與確定病例有呼吸道分泌物、體液之直接接觸。二、具有確定病例或極可能病例所在地區之旅遊史。


疾病分類(Case classification):
調查病例(Person under investigation)符合臨床條件及流行病學條件。

極可能病例(Probable case): 符合臨床條件,且經檢驗為流感病毒A型陽性,惟其亞型無法以季節性流感之檢測方法分型,或符合臨床條件及流行病學條件,或不明原因之急性呼吸道症狀死亡之個案,與極可能或確定病例具有流行病學之關聯。

確定病例(Confirmed case):符合臨床條件及檢驗條件。


資訊來源:
臺大校訊第962期


[H1N1] National Taiwan University Newsletter Defines H1N1 Novel Influenza

The present issue (Issue 962) of National Taiwan University Newsletter announces the definition of H1N1 novel influenza, providing criteria of three kinds (clinical, laboratory and epidemiological) to serve as classification standard for the cases.

Clinical criteria: Featuring acute ferbrile respiratory illness, fever over 100.4 ℉, and the clinical syndrome observed to be similar with those distributed from slight influenza-like illness to severe pneumonia.

Laboratory criteria: Tested by the subordinated or contracted laboratories of the central authorities as H1N1 novel influenza virus positive, and the testing method is one of the following: 1. real-time RT-PRC, 2. virus culture, and 3. the neutralizing antibodies of H1N1 novel influenza virus four-times upgrading. The testing methods have to be carried out under the latest testing guidelines.

Epidemiology criteria: (one of the following)

1. Having close contact with confirmed or probable case, such as nursing, living together, or direct contacts with the confirmed case' secretion of the respiratory tract or body fluid. 2. Travel history in the areas of confirmed or probable cases reported.


Case classification:
Person under investigation conform ing to clinical criteria and epidemical criteria.

Probable case: In conformity to the clinical criteria, and testified influenza virus A model, whose subpopulation however could not be classified with the testing method of seasonal influenza; in conformity to the clinical and epidemical criteria; or unidentified cause of death with acute respiratory syndrome; or in epidemical connection with probable or confirmed case.

Confirmed case: In conformity to clinical and laboratory criteria.


Reference:
National Taiwan University Newsletter Issue 962 (Chinese)



Edited 1 time(s). Last edit at 05/08/2009 01:33AM by gustav.
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